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Rev. chil. med. intensiv ; 23(1): 43-48, 2008. ilus, tab, graf
Article in Spanish | LILACS | ID: lil-516208

ABSTRACT

La sepsis grave en pacientes quirúrgicos tiene una mortalidad elevada. Hay evidencias que el uso de proteína C activada recombinante (Drotrecogin alfa) mejora la sobrevida en estos pacientes. Presentamos el caso de un hombre de 40 años con síndrome de Marfán sometido a cirugía cardiaca valvular que desarrolla sepsis grave por lo cual se administra proteína C activada recombinante con resultados favorables.


Severe sepsis in surgical patients has a high mortality. There is evidence that the use of recombinant human activated protein C (Drotrecogin alfa) improves survival in these patients. We report the use of drotrecogin alfa, in a 40-year-old male with Marfan’s syndrome undergone cardiac valve surgery that develops severe sepsis, with good results.


Subject(s)
Humans , Male , Middle Aged , Protein C/therapeutic use , Recombinant Proteins/therapeutic use , Sepsis/drug therapy , Postoperative Period
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